Cell-free DNA for the detection of kidney allograft rejection

Aubert O, Ursule-Dufait C, Brousse R, Gueguen J, Racapé M, Raynaud M,  Van Loon E, Pagliazzi A, Huang E, Jordan S-C, Chavin K-D, Gupta G, Kumar D, Alhamad Y, Anand S, Sanchez-Garcia J, Abdalla B-A, Hogan J, Garro R, Dadhania D-M, Jain P, Mandelbrot D-A, Naesens M, Dandamudi R, Dharnidharka V-R, Anglicheau D, Lefaucheur C, Loupy A

Nature Medicine, June 2024. | DOI : 10.1038/s41591-024-03087-3 | PMID: 38824959

Design, cohort profile and comparison of the KTD-Innov study: a prospective multidimensional biomarker validation study in kidney allograft rejection

Goutaudier V, Sablik M, Racapé M, Rousseau O, Audry B, Kamar N, Raynaud M, Aubert O, Charreau B, Papuchon E, Danger R, Letertre L, Couzi L, Morelon E, Le Quintrec M, Taupin J-L, Vicaut E, Legendre C, Le Mai H, Potluri V, Nguyen T-V-H, Azoury M-E, Pinheiro A, Nouadje G, Sonigo P, Anglicheau D, Tieken I, Vogelaar S, Jacquelinet C, Reese P, Gourraud P-A, Brouard S, Lefaucheur C, Loupy A on behalf of the KTD-Innov Consortium.

European Journal of Epidemiology, April 2024. | DOI: 10.1007/s10654-024-01112-w | PMID: 38625480

Prognostic Biomarkers in Kidney Transplantation: A Systematic Review and Critical Appraisal

Raynaud M, Al-Awadhi S, Louis K, Zhang H, Su X, Goutaudier V, Wang J, Demir Z, Wei Y, Truchot A, Bouquegneau A, Del Bello A, Bailly É, Lombardi Y,
Maanaoui M, Giarraputo A, Naser S, Divard G, Aubert O, Murad Mohammad H, Wang C, Liu L, Bestard O, Naesens M, Friedewald J, Lefaucheur C, Riella L, Collins G, Ioannidis P.A. J, Loupy A.

Journal of the American Society of Nephrology 35(2):p 177-188, February 2024. | DOI: 10.1681/ASN.0000000000000260 | PMID: 38053242

Identification of liver transplant biopsy phenotypes associated with distinct liver biological markers and allograft survival

Demir Z, Raynaud M, Aubert O, Debray D, Sebagh M, Duong Van Huyen J-P, Del Bello A, Congy Jolivet N, Paradis V, Durand F, Muratot S, Lozach C, Chardot C, Francoz C, Kamar N, Sarnacki S, Coilly A, Samuel D, Vibert E, Feray C*, Lefaucheur C*, Loupy A*.

Am J Transplant. 2023 Dec 12:S1600-6135(23)00907-3. doi: 10.1016/j.ajt.2023.12.007. Online ahead of print. PMID: 38097016

Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study.

Loupy A, Goutaudier V, Giarraputo A, Mezine F, Morgand E, Robin B, Khalil K, Mehta S, Keating B, Dandro A, Certain A, Tharaux PL, Narula N, Tissier R, Giraud S, Hauet T, Pass HI, Sannier A, Wu M, Griesemer A, Ayares D, Tatapudi V, Stern J, Lefaucheur C, Bruneval P, Mangiola M, Montgomery RA.

Lancet. 2023 Aug 17:S0140-6736(23)01349-1. doi: 10.1016/S0140-6736(23)01349-1. Online ahead of print.PMID: 37598688

Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.

Raynaud M, Al-Awadhi S, Juric I, Divard G, Lombardi Y, Basic-Jukic N, Aubert O, Dubourg L, Masson I, Mariat C, Prié D, Pernin V, Le Quintrec M, Larson TS, Stegall MD, Bikbov B, Ruggenenti P, Mesnard L, Ibrahim HN, Nielsen MB, Matas AJ, Nankivell BJ, Benjamens S, Pol RA, Bakker SJL, Jouven X, Legendre C, Kamar N, Smith BH, Wadei HM, Durrbach A, Vincenti F, Remuzzi G, Lefaucheur C, Bentall AJ, Loupy A.

BMJ. 2023 May 31;381:e073654. doi: 10.1136/bmj-2022-073654.PMID: 37257905 

Excess mortality after kidney transplantation: does sex matter?

Truchot A, Raynaud M, Loupy A.

Kidney Int. 2023 Jun;103(6):1023-1024. doi: 10.1016/j.kint.2023.03.011.PMID: 37210193

An automated histological classification system for precision diagnostics of kidney allografts.

Yoo D, Goutaudier V, Divard G, Gueguen J, Astor BC, Aubert O, Raynaud M, Demir Z, Hogan J, Weng P, Smith J, Garro R, Warady BA, Zahr RS, Sablik M, Twombley K, Couzi L, Berney T, Boyer O, Duong-Van-Huyen JP, Giral M, Alsadi A, Gourraud PA, Morelon E, Le Quintrec M, Brouard S, Legendre C, Anglicheau D, Villard J, Zhong W, Kamar N, Bestard O, Djamali A, Budde K, Haas M, Lefaucheur C, Rabant M, Loupy A.

Nat Med. 2023 May 4. doi: 10.1038/s41591-023-02323-6. Online ahead of print.PMID: 37142762

Machine learning does not outperform traditional statistical modelling for kidney allograft failure prediction.

Truchot A, Raynaud M, Kamar N, Naesens M, Legendre C, Delahousse M, Thaunat O, Buchler M, Crespo M, Linhares K, Orandi BJ, Akalin E, Pujol GS, Silva HT Jr, Gupta G, Segev DL, Jouven X, Bentall AJ, Stegall MD, Lefaucheur C, Aubert O, Loupy A.

Kidney Int. 2023 May;103(5):936-948. doi: 10.1016/j.kint.2022.12.011. Epub 2022 Dec 23.PMID: 36572246

Quantitative scoring of progression in transplant glomerulopathy using digital pathology may be superior to Banff cg scoring.

Kikić Ž, Adam BA, Porras AB, Lefaucheur C, Loupy A, Regele H, Cejka D, Haas M, Colvin RB, Mengel M.

Kidney Int. 2023 Feb;103(2):365-377. doi: 10.1016/j.kint.2022.10.024. Epub 2022 Nov 25.PMID: 36436680

Outcomes in kidney transplant recipients treated with immediate-release tacrolimus capsules versus extended-release tacrolimus capsules: A cohort study.

Ha YP, Divard G, Mitra N, Putt ME, Pallet N, Loupy A, Anglicheau D, Trofe-Clark J, Legendre C, Bloom RD, Reese PP.

Clin Transplant. 2023 Jan;37(1):e14840. doi: 10.1111/ctr.14840. Epub 2022 Nov 27.PMID: 36374204.

Thirty years of the International Banff Classification for Allograft Pathology: the past, present, and future of kidney transplant diagnostics.

Loupy A, Mengel M, Haas M.

Kidney Int. 2022 Apr;101(4):678-691. doi: 10.1016/j.kint.2021.11.028. Epub 2021 Dec 17.

PMID: 34922989 

Surrogate Endpoints for Late Kidney Transplantation Failure.

Naesens M, Budde K, Hilbrands L, Oberbauer R, Bellini MI, Glotz D, Grinyó J, Heemann U, Jochmans I, Pengel L, Reinders M, Schneeberger S, Loupy A.

Transpl Int. 2022 May 20;35:10136. doi: 10.3389/ti.2022.10136. eCollection 2022.

PMID: 35669974

Allograft Function as Endpoint for Clinical Trials in Kidney Transplantation.

Hilbrands L, Budde K, Bellini MI, Diekmann F, Furian L, Grinyó J, Heemann U, Hesselink DA, Loupy A, Oberbauer R, Pengel L, Reinders M, Schneeberger S, Naesens M.

Transpl Int. 2022 May 20;35:10139. doi: 10.3389/ti.2022.10139. eCollection 2022.

Proposed Definitions of T Cell-Mediated Rejection and Tubulointerstitial Inflammation as Clinical Trial Endpoints in Kidney Transplantation.

Seron D, Rabant M, Becker JU, Roufosse C, Bellini MI, Böhmig GA, Budde K, Diekmann F, Glotz D, Hilbrands L, Loupy A, Oberbauer R, Pengel L, Schneeberger S, Naesens M.

Transpl Int. 2022 May 20;35:10135. doi: 10.3389/ti.2022.10135. eCollection 2022.

PMID: 35669975 

New Equations for Estimating the GFR without Race.

Raynaud M, Aubert O, Loupy A.

N Engl J Med. 2022 Apr 28;386(17):1669-1670. doi: 10.1056/NEJMc2119761. PMID: 35476657

mTOR signaling cascade: novel clinical implications in HLA and non-HLA antibody-mediated vasculopathies?

Louis K, Loupy A, Lefaucheur C.Kidney Int. 2022 Mar;101(3):451-454. doi: 10.1016/j.kint.2021.12.008.PMID: 35190030

Data-Driven Chronic Allograft Phenotypes: A Novel and Validated Complement for Histologic Assessment of Kidney Transplant Biopsies.

Vaulet T, Divard G, Thaunat O, Koshy P, Lerut E, Senev A, Aubert O, Van Loon E, Callemeyn J, Emonds MP, Van Craenenbroeck A, De Vusser K, Sprangers B, Rabeyrin M, Dubois V, Kuypers D, De Vos M, Loupy A, De Moor B, Naesens M.

J Am Soc Nephrol. 2022 Nov;33(11):2026-2039. doi: 10.1681/ASN.2022030290. Epub 2022 Sep 7.

Clinical Prediction Model for Antibody-Mediated Rejection: A Strategy to Minimize Surveillance Endomyocardial Biopsies After Heart Transplantation.

Coutance G, Kransdorf E, Aubert O, Bonnet G, Yoo D, Rouvier P, Duong Van Huyen JP, Bruneval P, Taupin JL, Leprince P, Varnous S, Kobashigawa J, Jouven X, Patel J, Loupy A. Circ Heart Fail. 2022 Oct;15(10):e009923. doi: 10.1161/CIRCHEARTFAILURE.122.009923. Epub 2022 Oct 6.PMID: 36200456.

Comparison of artificial intelligence and human-based prediction and stratification of the risk of long-term kidney allograft failure.

Divard G, Raynaud M, Tatapudi VS, Abdalla B, Bailly E, Assayag M, Binois Y, Cohen R, Zhang H, Ulloa C, Linhares K, Tedesco HS, Legendre C, Jouven X, Montgomery RA, Lefaucheur C, Aubert O, Loupy A. Commun Med (Lond). 2022 Nov 23;2(1):150. doi: 10.1038/s43856-022-00201-9.PMID: 36418380.

COVID-19 pandemic and worldwide organ transplantation: a population-based study.

Aubert O, Yoo D, Zielinski D, Cozzi E, Cardillo M, Dürr M, Domínguez-Gil B, Coll E, Da Silva MI, Sallinen V, Lemström K, Midtvedt K, Ulloa C, Immer F, Weissenbacher A, Vallant N, Basic-Jukic N, Tanabe K, Papatheodoridis G, Menoudakou G, Torres M, Soratti C, Hansen Krogh D, Lefaucheur C, Ferreira G, Silva HT Jr, Hartell D, Forsythe J, Mumford L, Reese PP, Kerbaul F, Jacquelinet C, Vogelaar S, Papalois V, Loupy A. Lancet Public Health. 2021 Oct;6(10):e709-e719. doi: 10.1016/S2468-2667(21)00200-0. Epub 2021 Aug 30. PMID: 34474014

Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study.

Raynaud M, Aubert O, Divard G, Reese PP, Kamar N, Yoo D, Chin CS, Bailly É, Buchler M, Ladrière M, Le Quintrec M, Delahousse M, Juric I, Basic-Jukic N, Crespo M, Silva HT Jr, Linhares K, Ribeiro de Castro MC, Soler Pujol G, Empana JP, Ulloa C, Akalin E, Böhmig G, Huang E, Stegall MD, Bentall AJ, Montgomery RA, Jordan SC, Oberbauer R, Segev DL, Friedewald JJ, Jouven X, Legendre C, Lefaucheur C, Loupy A.

Lancet Digit Health. 2021 Dec;3(12):e795-e805. doi: 10.1016/S2589-7500(21)00209-0. Epub 2021 Oct 28.

PMID: 34756569 

COVID-19-related medical research: a meta-research and critical appraisal.

Raynaud M, Zhang H, Louis K, Goutaudier V, Wang J, Dubourg Q, Wei Y, Demir Z, Debiais C, Aubert O, Bouatou Y, Lefaucheur C, Jabre P, Liu L, Wang C, Jouven X, Reese P, Empana JP, Loupy A.

BMC Med Res Methodol. 2021 Jan 4;21(1):1. doi: 10.1186/s12874-020-01190-w.

Solid organ procurement and transplantation from deceased donors with vaccine-induced thrombosis and thrombocytopenia.

Loupy A, Goutaudier V, Jacquelinet C, Kerbaul F.Am J Transplant. 2021 Dec;21(12):4098-4101. doi: 10.1111/ajt.16751. Epub 2021 Jul 17.

The emerging field of non-human leukocyte antigen antibodies in transplant medicine and beyond.

Lefaucheur C, Louis K, Philippe A, Loupy A, Coates PT.Kidney Int. 2021 Oct;100(4):787-798. doi: 10.1016/j.kint.2021.04.044. Epub 2021 Jun 26.PMID: 34186057 

Complement inhibition for prevention of antibody-mediated rejection in immunologically high-risk heart allograft recipients.

Patel JK, Coutance G, Loupy A, Dilibero D, Hamilton M, Kittleson M, Kransdorf E, Azarbal B, Seguchi O, Zhang X, Chang D, Geft D, Czer L, Varnous S, Kobashigawa JA.Am J Transplant. 2021 Jul;21(7):2479-2488. doi: 10.1111/ajt.16420. Epub 2021 Feb 11.PMID: 33251691

Statistical performance of 16 posttransplant risk scores in a contemporary cohort of heart transplant recipients.

Coutance G, Kransdorf E, Bonnet G, Loupy A, Kobashigawa J, Patel JK.Am J Transplant. 2021 Feb;21(2):645-656. doi: 10.1111/ajt.16217. Epub 2020 Sep 5.PMID: 32713121 

Data-driven Derivation and Validation of Novel Phenotypes for Acute Kidney Transplant Rejection using Semi-supervised Clustering.

Vaulet T, Divard G, Thaunat O, Lerut E, Senev A, Aubert O, Van Loon E, Callemeyn J, Emonds MP, Van Craenenbroeck A, De Vusser K, Sprangers B, Rabeyrin M, Dubois V, Kuypers D, De Vos M, Loupy A, De Moor B, Naesens M.J Am Soc Nephrol. 2021 May 3;32(5):1084-1096. doi: 10.1681/ASN.2020101418. Epub 2021 Mar 9.PMID: 33687976 

Trajectories of glomerular filtration rate and progression to end stage kidney disease after kidney transplantation.

Raynaud M, Aubert O, Reese PP, Bouatou Y, Naesens M, Kamar N, Bailly É, Giral M, Ladrière M, Le Quintrec M, Delahousse M, Juric I, Basic-Jukic N, Gupta G, Akalin E, Yoo D, Chin CS, Proust-Lima C, Böhmig G, Oberbauer R, Stegall MD, Bentall AJ, Jordan SC, Huang E, Glotz D, Legendre C, Montgomery RA, Segev DL, Empana JP, Grams ME, Coresh J, Jouven X, Lefaucheur C, Loupy A. Kidney Int. 2021 Jan;99(1):186-197. doi: 10.1016/j.kint.2020.07.025. Epub 2020 Aug 8.PMID: 32781106

Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the United States: A Comparison of International Transplant Practices and Outcomes.

Reese PP, Aubert O, Naesens M, Huang E, Potluri V, Kuypers D, Bouquegneau A, Divard G, Raynaud M, Bouatou Y, Vo A, Glotz D, Legendre C, Lefaucheur C, Jordan S, Empana JP, Jouven X, Loupy A. J Am Soc Nephrol. 2021 Feb;32(2):397-409. doi: 10.1681/ASN.2020040464. Epub 2020 Dec 15.PMID: 33323474 

Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study.

Aubert O, Divard G, Pascual J, Oppenheimer F, Sommerer C, Citterio F, Tedesco H, Chadban S, Henry M, Vincenti F, Srinivas T, Watarai Y, Legendre C, Bernhardt P, Loupy A. BMJ Open. 2021 Oct 7;11(10):e052138. doi: 10.1136/bmjopen-2021-052138.PMID: 34620664 

Impact of the COVID-19 pandemic on publication dynamics and non-COVID-19 research production.

Raynaud M, Goutaudier V, Louis K, Al-Awadhi S, Dubourg Q, Truchot A, Brousse R, Saleh N, Giarraputo A, Debiais C, Demir Z, Certain A, Tacafred F, Cortes-Garcia E, Yanes S, Dagobert J, Naser S, Robin B, Bailly É, Jouven X, Reese PP, Loupy A. BMC Med Res Methodol. 2021 Nov 22;21(1):255. doi: 10.1186/s12874-021-01404-9.PMID: 34809561 

Development and validation of specific post-transplant risk scores according to the circulatory support status at transplant: A UNOS cohort analysis.

Coutance G, Bonnet G, Kransdorf EP, Loupy A, Moriguchi J, Leprince P, Kobashigawa JA, Patel JK.J Heart Lung Transplant. 2021 Oct;40(10):1235-1246. doi: 10.1016/j.healun.2021.06.010. Epub 2021 Jun 24.PMID: 34274182

Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the United States: A Comparison of International Transplant Practices and Outcomes.
Reese PP, Aubert O, Naesens M, Huang E, Potluri V, Kuypers D, Bouquegneau A, Divard G, Raynaud M, Bouatou Y, Vo A, Glotz D, Legendre C, Lefaucheur C, Jordan S, Empana JP, Jouven X, Loupy A.
J Am Soc Nephrol. 2021 Feb;32(2):397-409. doi: 10.1681/ASN.2020040464. Epub 2020 Dec 15.PMID: 33323474

Response by Coutance et al to Letter Regarding Article, « Identification and Characterization of Trajectories of Cardiac Allograft Vasculopathy After Heart Transplantation: A Population-Based Study ».
Coutance G, Raynaud M, Patel JK, Kobashigawa JA, Loupy A.
Circulation. 2020 Dec 8;142(23):e409-e410. doi: 10.1161/CIRCULATIONAHA.120.050849. Epub 2020 Dec 7.PMID: 33284650 No abstract available.

Complement inhibition for prevention of antibody-mediated rejection in immunologically high-risk heart allograft recipients.
Patel JK, Coutance G, Loupy A, Dilibero D, Hamilton M, Kittleson M, Kransdorf E, Azarbal B, Seguchi O, Zhang X, Chang D, Geft D, Czer L, Varnous S, Kobashigawa JA.
Am J Transplant. 2020 Nov 29. doi: 10.1111/ajt.16420. Online ahead of print.PMID: 33251691

Does the definition of chronic active T cell-mediated rejection need revisiting?
Naesens M, Haas M, Loupy A, Roufosse C, Mengel M.
Am J Transplant. 2021 May;21(5):1689-1690. doi: 10.1111/ajt.16419. Epub 2020 Dec 22.PMID: 33249773

An International survey on living kidney donation and transplant practices during the COVID-19 pandemic.
Salvalaggio PR, Ferreira GF, Caliskan Y, Vest LS, Schnitzler MA, de Sandes-Freitas TV, Moura LR, Lam NN, Maldonado RA, Loupy A, Axelrod DA, Lentine KL.
Transpl Infect Dis. 2021 Apr;23(2):e13526. doi: 10.1111/tid.13526. Epub 2020 Dec 19.PMID: 33245844 

Trajectories of glomerular filtration rate and progression to end stage kidney disease after kidney transplantation.
Raynaud M, Aubert O, Reese PP, Bouatou Y, Naesens M, Kamar N, Bailly É, Giral M, Ladrière M, Le Quintrec M, Delahousse M, Juric I, Basic-Jukic N, Gupta G, Akalin E, Yoo D, Chin CS, Proust-Lima C, Böhmig G, Oberbauer R, Stegall MD, Bentall AJ, Jordan SC, Huang E, Glotz D, Legendre C, Montgomery RA, Segev DL, Empana JP, Grams ME, Coresh J, Jouven X, Lefaucheur C, Loupy A.
Kidney Int. 2021 Jan;99(1):186-197. doi: 10.1016/j.kint.2020.07.025. Epub 2020 Aug 8.PMID: 32781106

Statistical performance of 16 posttransplant risk scores in a contemporary cohort of heart transplant recipients.
Coutance G, Kransdorf E, Bonnet G, Loupy A, Kobashigawa J, Patel JK.
Am J Transplant. 2021 Feb;21(2):645-656. doi: 10.1111/ajt.16217. Epub 2020 Sep 5.PMID: 32713121

The XVth Banff Conference on Allograft Pathology the Banff Workshop Heart Report: Improving the diagnostic yield from endomyocardial biopsies and Quilty effect revisited.
Duong Van Huyen JP, Fedrigo M, Fishbein GA, Leone O, Neil D, Marboe C, Peyster E, von der Thüsen J, Loupy A, Mengel M, Revelo MP, Adam B, Bruneval P, Angelini A, Miller DV, Berry GJ.
Am J Transplant. 2020 Dec;20(12):3308-3318. doi: 10.1111/ajt.16083. Epub 2020 Jun 28.PMID: 32476272

The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell- and antibody-mediated rejection.
Loupy A, Haas M, Roufosse C, Naesens M, Adam B, Afrouzian M, Akalin E, Alachkar N, Bagnasco S, Becker JU, Cornell LD, Clahsen-van Groningen MC, Demetris AJ, Dragun D, Duong van Huyen JP, Farris AB, Fogo AB, Gibson IW, Glotz D, Gueguen J, Kikic Z, Kozakowski N, Kraus E, Lefaucheur C, Liapis H, Mannon RB, Montgomery RA, Nankivell BJ, Nickeleit V, Nickerson P, Rabant M, Racusen L, Randhawa P, Robin B, Rosales IA, Sapir-Pichhadze R, Schinstock CA, Seron D, Singh HK, Smith RN, Stegall MD, Zeevi A, Solez K, Colvin RB, Mengel M.
Am J Transplant. 2020 Sep;20(9):2318-2331. doi: 10.1111/ajt.15898. Epub 2020 May 28.PMID: 32463180 

Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation-Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation.
Mengel M, Loupy A, Haas M, Roufosse C, Naesens M, Akalin E, Clahsen-van Groningen MC, Dagobert J, Demetris AJ, Duong van Huyen JP, Gueguen J, Issa F, Robin B, Rosales I, Von der Thüsen JH, Sanchez-Fueyo A, Smith RN, Wood K, Adam B, Colvin RB.
Am J Transplant. 2020 Sep;20(9):2305-2317. doi: 10.1111/ajt.16059. Epub 2020 Jun 27.PMID: 32428337

Organ procurement and transplantation during the COVID-19 pandemic.
Loupy A, Aubert O, Reese PP, Bastien O, Bayer F, Jacquelinet C.
Lancet. 2020 May 23;395(10237):e95-e96. doi: 10.1016/S0140-6736(20)31040-0. Epub 2020 May 11.PMID: 32407668 

Intragraft gene expression in native kidney BK virus nephropathy versus T cell-mediated rejection: Prospects for molecular diagnosis and risk prediction.
Adam BA, Kikic Z, Wagner S, Bouatou Y, Gueguen J, Drieux F, Reid G, Du K, Bräsen JH, D’Agati VD, Drachenberg CB, Farkash EA, Brad Farris A, Geldenhuys L, Loupy A, Nickeleit V, Rabant M, Randhawa P, Regele H, Mengel M.
Am J Transplant. 2020 Dec;20(12):3486-3501. doi: 10.1111/ajt.15980. Epub 2020 May 29.PMID: 32372431

Identification and Characterization of Trajectories of Cardiac Allograft Vasculopathy After Heart Transplantation: A Population-Based Study.
Loupy A, Coutance G, Bonnet G, Van Keer J, Raynaud M, Aubert O, Bories MC, Racapé M, Yoo D, Duong Van Huyen JP, Bruneval P, Taupin JL, Lefaucheur C, Varnous S, Leprince P, Guillemain R, Empana JP, Levine R, Naesens M, Patel JK, Jouven X, Kobashigawa J.
Circulation. 2020 Jun 16;141(24):1954-1967. doi: 10.1161/CIRCULATIONAHA.119.044924. Epub 2020 May 4.PMID: 32363949

Association of HLA Typing and Alloimmunity With Posttransplantation Membranous Nephropathy: A Multicenter Case Series.
Batal I, Vasilescu ER, Dadhania DM, Adel AA, Husain SA, Avasare R, Serban G, Santoriello D, Khairallah P, Patel A, Moritz MJ, Latulippe E, Riopel J, Khallout K, Swanson SJ, Bomback AS, Mohan S, Ratner L, Radhakrishnan J, Cohen DJ, Appel GB, Stokes MB, Markowitz GS, Seshan SV, De Serres SA, Andeen N, Loupy A, Kiryluk K, D’Agati VD.
Am J Kidney Dis. 2020 Sep;76(3):374-383. doi: 10.1053/j.ajkd.2020.01.009. Epub 2020 Apr 28.PMID: 32359820

The Number of Discarded Kidneys Is Likely Much Larger Than Reported-Reply.
Reese PP, Aubert O, Loupy A.
JAMA Intern Med. 2020 Mar 1;180(3):467-468. doi: 10.1001/jamainternmed.2019.6099.PMID: 32119050 

Use of biomarkers to improve immunosuppressive drug development and outcomes in renal organ transplantation: A meeting report.
Mannon RB, Morris RE, Abecassis M, Axelrod D, Bala S, Friedman GS, Heeger PS, Lentine KL, Loupy A, Murphy B, Nickerson P, Sarwal M, O’Doherty I, Spear N, Karpen SR.
Am J Transplant. 2020 Jun;20(6):1495-1502. doi: 10.1111/ajt.15833. Epub 2020 Mar 17.PMID: 32090461

Reverse transcriptase multiplex ligation-dependent probe amplification in endomyocardial biopsies for the diagnosis of cardiac allograft rejection.
Adam N, Coutance G, Viailly PJ, Drieux F, Ruminy P, Sater AA, Toquet C, Rouvier P, François A, Chenard MP, Epailly E, Guillemain R, Pattier S, Gay A, Varnous S, Taupin JL, Rabant M, Loupy A, Bruneval P, Duong Van Huyen JP.
J Heart Lung Transplant. 2020 Feb;39(2):115-124. doi: 10.1016/j.healun.2019.11.010. Epub 2019 Nov 26.PMID: 31822443

In situ multiplex immunofluorescence analysis of the inflammatory burden in kidney allograft rejection: A new tool to characterize the alloimmune response.
Calvani J, Terada M, Lesaffre C, Eloudzeri M, Lamarthée B, Burger C, Tinel C, Anglicheau D, Vermorel A, Couzi L, Loupy A, Duong Van Huyen JP, Bruneval P, Rabant M.
​Am J Transplant. 2020 Apr;20(4):942-953. doi: 10.1111/ajt.15699. Epub 2019 Dec 11.PMID: 31715060

Reverse transcriptase multiplex ligation-dependent probe amplification in endomyocardial biopsies for the diagnosis of cardiac allograft rejection.
Adam N, Coutance G, Viailly PJ, Drieux F, Ruminy P, Sater AA, Toquet C, Rouvier P, François A, Chenard MP, Epailly E, Guillemain R, Pattier S, Gay A, Varnous S, Taupin JL, Rabant M, Loupy A, Bruneval P, Duong Van Huyen JP.
J Heart Lung Transplant. 2020 Feb;39(2):115-124. doi: 10.1016/j.healun.2019.11.010. Epub 2019 Nov 26.PMID: 31822443

Clinical outcomes after ABO-incompatible renal transplantation.
Loupy A, Bouquegneau A, Stegall MD, Montgomery RA.
Lancet. 2019 Nov 30;394(10213):1988-1989. doi: 10.1016/S0140-6736(19)32490-0.PMID: 31789213

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants.
Koenig A, Chen CC, Marçais A, Barba T, Mathias V, Sicard A, Rabeyrin M, Racapé M, Duong-Van-Huyen JP, Bruneval P, Loupy A, Dussurgey S, Ducreux S, Meas-Yedid V, Olivo-Marin JC, Paidassi H, Guillemain R, Taupin JL, Callemeyn J, Morelon E, Nicoletti A, Charreau B, Dubois V, Naesens M, Walzer T, Defrance T, Thaunat O.
Nat Commun. 2019 Nov 25;10(1):5350. doi: 10.1038/s41467-019-13113-5.PMID: 31767837

In situ multiplex immunofluorescence analysis of the inflammatory burden in kidney allograft rejection: A new tool to characterize the alloimmune response.
Calvani J, Terada M, Lesaffre C, Eloudzeri M, Lamarthée B, Burger C, Tinel C, Anglicheau D, Vermorel A, Couzi L, Loupy A, Duong Van Huyen JP, Bruneval P, Rabant M.
Am J Transplant. 2020 Apr;20(4):942-953. doi: 10.1111/ajt.15699. Epub 2019 Dec 11.PMID: 31715060

[Renal transplantation: Procedure and early follow-up].
Anglicheau D, Tinel C, Canaud G, Loupy A, Zuber J, Delville M, Rabaté C, Scemla A, Snanoudj R, Sberro-Soussan R, Mamzer-Bruneel MF, Bererhi L, Martinez F, Timsit MO, Rabant M, Correas JM, Bienaimé F, Duong JP, Hélénon O, Prié D, Méjean A, Legendre C.
Nephrol Ther. 2019 Nov;15(6):469-484. doi: 10.1016/j.nephro.2019.09.001. Epub 2019 Oct 19.PMID: 31640943 French.

Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study.
Loupy A, Aubert O, Orandi BJ, Naesens M, Bouatou Y, Raynaud M, Divard G, Jackson AM, Viglietti D, Giral M, Kamar N, Thaunat O, Morelon E, Delahousse M, Kuypers D, Hertig A, Rondeau E, Bailly E, Eskandary F, Böhmig G, Gupta G, Glotz D, Legendre C, Montgomery RA, Stegall MD, Empana JP, Jouven X, Segev DL, Lefaucheur C.
BMJ. 2019 Sep 17;366:l4923. doi: 10.1136/bmj.l4923.PMID: 31530561 Clinical Trial.

Disparities in Acceptance of Deceased Donor Kidneys Between the United States and France and Estimated Effects of Increased US Acceptance.
Aubert O, Reese PP, Audry B, Bouatou Y, Raynaud M, Viglietti D, Legendre C, Glotz D, Empana JP, Jouven X, Lefaucheur C, Jacquelinet C, Loupy A.
JAMA Intern Med. 2019 Oct 1;179(10):1365-1374. doi: 10.1001/jamainternmed.2019.2322.PMID: 31449299

Beyond Survival in Solid Organ Transplantation: A Summary of Expert Presentations from the Sandoz 6th Standalone Transplantation Meeting, 2018.
Legendre C, Viebahn R, Crespo M, Dor F, Gustafsson B, Samuel U, Karam V, Binet I, Aberg F, De Geest S, Moes DJAR, Tonshoff B, Oppenheimer F, Asberg A, Halleck F, Loupy A, Suesal C.
Transplantation. 2019 Sep;103(9 Suppl 1):S1-S13. doi: 10.1097/TP.0000000000002846.PMID: 31449167

Anti-IL-2R blockers comparing with polyclonal antibodies: Higher risk of rejection without negative mid-term outcomes after ABO-incompatible kidney transplantation.
Del Bello A, Divard G, Belliere J, Congy-Jolivet N, Lanfranco L, Ricard R, Delas A, Colombat M, Esposito L, Hebral AL, Cointault O, Lefaucheur C, Loupy A, Kamar N.
Clin Transplant. 2019 Oct;33(10):e13681. doi: 10.1111/ctr.13681. Epub 2019 Sep 8.PMID: 31369170

Non-HLA agonistic anti-angiotensin II type 1 receptor antibodies induce a distinctive phenotype of antibody-mediated rejection in kidney transplant recipients.
Lefaucheur C, Viglietti D, Bouatou Y, Philippe A, Pievani D, Aubert O, Duong Van Huyen JP, Taupin JL, Glotz D, Legendre C, Loupy A, Halloran PF, Dragun D.
Kidney Int. 2019 Jul;96(1):189-201. doi: 10.1016/j.kint.2019.01.030. Epub 2019 Mar 15.PMID: 31005275

Archetype Analysis Identifies Distinct Profiles in Renal Transplant Recipients with Transplant Glomerulopathy Associated with Allograft Survival.
Aubert O, Higgins S, Bouatou Y, Yoo D, Raynaud M, Viglietti D, Rabant M, Hidalgo L, Glotz D, Legendre C, Delahousse M, Shah N, Sis B, Campbell P, Mengel M, Jouven X, Duong Van Huyen JP, Lefaucheur C, Loupy A.J Am Soc Nephrol. 2019 Apr;30(4):625-639. doi: 10.1681/ASN.2018070777. Epub 2019 Mar 14.PMID: 30872323

An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms.
Parkes MD, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Halloran PF.
J Heart Lung Transplant. 2019 Jun;38(6):636-646. doi: 10.1016/j.healun.2019.01.1318. Epub 2019 Feb 6.PMID: 30795962

Modeling graft loss in patients with donor-specific antibody at baseline using the Birmingham-Mayo (BirMay) predictor: Implications for clinical trials.
Bentall A, Smith BH, Gonzales MM, Bonner K, Park WD, Cornell LD, Dean PG, Schinstock CA, Borrows R, Lefaucheur C, Loupy A, Stegall MD.
Am J Transplant. 2019 Aug;19(8):2274-2283. doi: 10.1111/ajt.15312. Epub 2019 Mar 13.PMID: 30768833

Response to treatment and long-term outcomes in kidney transplant recipients with acute T cell-mediated rejection.
Bouatou Y, Viglietti D, Pievani D, Louis K, Duong Van Huyen JP, Rabant M, Aubert O, Taupin JL, Glotz D, Legendre C, Loupy A, Lefaucheur C.
Am J Transplant. 2019 Jul;19(7):1972-1988. doi: 10.1111/ajt.15299. Epub 2019 Mar 15.PMID: 30748089

Towards a precision medicine approach to positive crossmatch transplantation: Impact on response to therapy.
Loupy A, Bouatou Y, Aubert O.Am J Transplant. 2019 Jun;19(6):1611-1613. doi: 10.1111/ajt.15271. Epub 2019 Feb 22.PMID: 30703855

Antibody-Mediated Rejection of Solid-Organ Allografts.
Lefaucheur C, Loupy A.
N Engl J Med. 2018 Dec 27;379(26):2580-2582. doi: 10.1056/NEJMc1813976.PMID: 30586534

Exploring the cardiac response to injury in heart transplant biopsies.
Halloran PF, Reeve J, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Jouven X, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Parkes MD.
JCI Insight. 2018 Oct 18;3(20):e123674. doi: 10.1172/jci.insight.123674.PMID: 30333303 

A 2018 Reference Guide to the Banff Classification of Renal Allograft Pathology.
Roufosse C, Simmonds N, Clahsen-van Groningen M, Haas M, Henriksen KJ, Horsfield C, Loupy A, Mengel M, Perkowska-Ptasińska A, Rabant M, Racusen LC, Solez K, Becker JU.
Transplantation. 2018 Nov;102(11):1795-1814. doi: 10.1097/TP.0000000000002366.PMID: 30028786 Review.

Complement-binding anti-HLA antibodies are independent predictors of response to treatment in kidney recipients with antibody-mediated rejection.
Viglietti D, Bouatou Y, Kheav VD, Aubert O, Suberbielle-Boissel C, Glotz D, Legendre C, Taupin JL, Zeevi A, Loupy A, Lefaucheur C.
Kidney Int. 2018 Oct;94(4):773-787. doi: 10.1016/j.kint.2018.03.015. Epub 2018 May 22.PMID: 29801667

Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis.
Bouquegneau A, Loheac C, Aubert O, Bouatou Y, Viglietti D, Empana JP, Ulloa C, Murad MH, Legendre C, Glotz D, Jackson AM, Zeevi A, Schaub S, Taupin JL, Reed EF, Friedewald JJ, Tyan DB, Süsal C, Shapiro R, Woodle ES, Hidalgo LG, O’Leary J, Montgomery RA, Kobashigawa J, Jouven X, Jabre P, Lefaucheur C, Loupy A.
PLoS Med. 2018 May 25;15(5):e1002572. doi: 10.1371/journal.pmed.1002572. eCollection 2018 May.PMID: 29799874 

A phase I/II, double-blind, placebo-controlled study assessing safety and efficacy of C1 esterase inhibitor for prevention of delayed graft function in deceased donor kidney transplant recipients.
Jordan SC, Choi J, Aubert O, Haas M, Loupy A, Huang E, Peng A, Kim I, Louie S, Ammerman N, Najjar R, Puliyanda D, Vo A.Am J Transplant. 2018 Dec;18(12):2955-2964. doi: 10.1111/ajt.14767. Epub 2018 May 14.PMID: 29637714 Clinical Trial.

The Human Cell Atlas Project by the numbers: Relationship to the Banff Classification.
Moghe I, Loupy A, Solez K.
Am J Transplant. 2018 Jul;18(7):1830. doi: 10.1111/ajt.14757. Epub 2018 Apr 21.PMID: 29607612 

[Identifying the specific causes of kidney allograft loss: A population-based study].
Lohéac C, Aubert O, Loupy A, Legendre C.
Nephrol Ther. 2018 Apr;14 Suppl 1:S39-S50. doi: 10.1016/j.nephro.2018.02.018.PMID: 29606262 French.

Post-Transplant Natural Antibodies Associate with Kidney Allograft Injury and Reduced Long-Term Survival.
See SB, Aubert O, Loupy A, Veras Y, Lebreton X, Gao B, Legendre C, Anglicheau D, Zorn E.
J Am Soc Nephrol. 2018 Jun;29(6):1761-1770. doi: 10.1681/ASN.2017111157. Epub 2018 Mar 30.PMID: 29602833 

Recognition of i-IF/TA as a component of the T cell-mediated rejection spectrum: Unselected population approach vs random case selection.
Lefaucheur C, Viglietti D, Loupy A.
Am J Transplant. 2018 Mar;18(3):771-772. doi: 10.1111/ajt.14667. Epub 2018 Jan 30.PMID: 29341409

Dynamic Prognostic Score to Predict Kidney Allograft Survival in Patients with Antibody-Mediated Rejection.
Viglietti D, Loupy A, Aubert O, Bestard O, Duong Van Huyen JP, Taupin JL, Glotz D, Legendre C, Jouven X, Delahousse M, Kamar N, Lefaucheur C.
J Am Soc Nephrol. 2018 Feb;29(2):606-619. doi: 10.1681/ASN.2017070749. Epub 2017 Dec 18.PMID: 29255058

Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection.
Chen CC, Pouliquen E, Broisat A, Andreata F, Racapé M, Bruneval P, Kessler L, Ahmadi M, Bacot S, Saison-Delaplace C, Marcaud M, Van Huyen JD, Loupy A, Villard J, Demuylder-Mischler S, Berney T, Morelon E, Tsai MK, Kolopp-Sarda MN, Koenig A, Mathias V, Ducreux S, Ghezzi C, Dubois V, Nicoletti A, Defrance T, Thaunat O.
J Clin Invest. 2018 Jan 2;128(1):219-232. doi: 10.1172/JCI93542. Epub 2017 Nov 20.PMID: 29202467

T cell-mediated rejection is a major determinant of inflammation in scarred areas in kidney allografts.
Lefaucheur C, Gosset C, Rabant M, Viglietti D, Verine J, Aubert O, Louis K, Glotz D, Legendre C, Duong Van Huyen JP, Loupy A.
Am J Transplant. 2018 Feb;18(2):377-390. doi: 10.1111/ajt.14565. Epub 2017 Nov 21.PMID: 29086461
 
Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment.
Lefaucheur C, Viglietti D, Hidalgo LG, Ratner LE, Bagnasco SM, Batal I, Aubert O, Orandi BJ, Oppenheimer F, Bestard O, Rigotti P, Reisaeter AV, Kamar N, Lebranchu Y, Duong Van Huyen JP, Bruneval P, Glotz D, Legendre C, Empana JP, Jouven X, Segev DL, Montgomery RA, Zeevi A, Halloran PF, Loupy A.
J Am Soc Nephrol. 2018 Feb;29(2):620-635. doi: 10.1681/ASN.2017050589. Epub 2017 Oct 17.PMID: 29042454

Dynamic Prognostic Score to Predict Kidney Allograft Survival in Patients with Antibody-Mediated Rejection.
Viglietti D, Loupy A, Aubert O, Bestard O, Duong Van Huyen JP, Taupin JL, Glotz D, Legendre C, Jouven X, Delahousse M, Kamar N, Lefaucheur C.
J Am Soc Nephrol. 2018 Feb;29(2):606-619. doi: 10.1681/ASN.2017070749. Epub 2017 Dec 18.PMID: 29255058

Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection.
Chen CC, Pouliquen E, Broisat A, Andreata F, Racapé M, Bruneval P, Kessler L, Ahmadi M, Bacot S, Saison-Delaplace C, Marcaud M, Van Huyen JD, Loupy A, Villard J, Demuylder-Mischler S, Berney T, Morelon E, Tsai MK, Kolopp-Sarda MN, Koenig A, Mathias V, Ducreux S, Ghezzi C, Dubois V, Nicoletti A, Defrance T, Thaunat O.
J Clin Invest. 2018 Jan 2;128(1):219-232. doi: 10.1172/JCI93542. Epub 2017 Nov 20.PMID: 29202467

T cell-mediated rejection is a major determinant of inflammation in scarred areas in kidney allografts.
Lefaucheur C, Gosset C, Rabant M, Viglietti D, Verine J, Aubert O, Louis K, Glotz D, Legendre C, Duong Van Huyen JP, Loupy A.
Am J Transplant. 2018 Feb;18(2):377-390. doi: 10.1111/ajt.14565. Epub 2017 Nov 21.PMID: 29086461

Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment.
Lefaucheur C, Viglietti D, Hidalgo LG, Ratner LE, Bagnasco SM, Batal I, Aubert O, Orandi BJ, Oppenheimer F, Bestard O, Rigotti P, Reisaeter AV, Kamar N, Lebranchu Y, Duong Van Huyen JP, Bruneval P, Glotz D, Legendre C, Empana JP, Jouven X, Segev DL, Montgomery RA, Zeevi A, Halloran PF, Loupy A.
J Am Soc Nephrol. 2018 Feb;29(2):620-635. doi: 10.1681/ASN.2017050589. Epub 2017 Oct 17.PMID: 29042454

Building a tissue-based molecular diagnostic system in heart transplant rejection: The heart Molecular Microscope Diagnostic (MMDx) System.
Halloran PF, Potena L, Van Huyen JD, Bruneval P, Leone O, Kim DH, Jouven X, Reeve J, Loupy A.
J Heart Lung Transplant. 2017 Nov;36(11):1192-1200. doi: 10.1016/j.healun.2017.05.029. Epub 2017 May 29.PMID: 28662985

Assessing rejection-related disease in kidney transplant biopsies based on archetypal analysis of molecular phenotypes.
Reeve J, Böhmig GA, Eskandary F, Einecke G, Lefaucheur C, Loupy A, Halloran PF; MMDx-Kidney study group.
JCI Insight. 2017 Jun 15;2(12):e94197. doi: 10.1172/jci.insight.94197. eCollection 2017 Jun 15.PMID: 28614805

Circulating donor-specific anti-HLA antibodies are a major factor in premature and accelerated allograft fibrosis.
Gosset C, Viglietti D, Rabant M, Vérine J, Aubert O, Glotz D, Legendre C, Taupin JL, Duong Van-Huyen JP, Loupy A, Lefaucheur C.
Kidney Int. 2017 Sep;92(3):729-742. doi: 10.1016/j.kint.2017.03.033. Epub 2017 May 26.PMID: 28554738

Antibody-Mediated Rejection Due to Preexisting versus De Novo Donor-Specific Antibodies in Kidney Allograft Recipients.
Aubert O, Loupy A, Hidalgo L, Duong van Huyen JP, Higgins S, Viglietti D, Jouven X, Glotz D, Legendre C, Lefaucheur C, Halloran PF.
J Am Soc Nephrol. 2017 Jun;28(6):1912-1923. doi: 10.1681/ASN.2016070797. Epub 2017 Mar 2.PMID: 28255002

Gene Expression Profiling for the Identification and Classification of Antibody-Mediated Heart Rejection.
Loupy A, Duong Van Huyen JP, Hidalgo L, Reeve J, Racapé M, Aubert O, Venner JM, Falmuski K, Bories MC, Beuscart T, Guillemain R, François A, Pattier S, Toquet C, Gay A, Rouvier P, Varnous S, Leprince P, Empana JP, Lefaucheur C, Bruneval P, Jouven X, Halloran PF.
Circulation. 2017 Mar 7;135(10):917-935. doi: 10.1161/CIRCULATIONAHA.116.022907. Epub 2017 Feb 1.PMID: 28148598

Long-term Outcomes of Kidney Transplantation in Patients With High Levels of Preformed DSA: The Necker High-Risk Transplant Program.
Amrouche L, Aubert O, Suberbielle C, Rabant M, Van Huyen JD, Martinez F, Sberro-Soussan R, Scemla A, Tinel C, Snanoudj R, Zuber J, Cavalcanti R, Timsit MO, Lamhaut L, Anglicheau D, Loupy A, Legendre C.
Transplantation. 2017 Oct;101(10):2440-2448. doi: 10.1097/TP.0000000000001650.PMID: 28114171

Value of Donor-Specific Anti-HLA Antibody Monitoring and Characterization for Risk Stratification of Kidney Allograft Loss.
Viglietti D, Loupy A, Vernerey D, Bentlejewski C, Gosset C, Aubert O, Duong van Huyen JP, Jouven X, Legendre C, Glotz D, Zeevi A, Lefaucheur C.
J Am Soc Nephrol. 2017 Feb;28(2):702-715. doi: 10.1681/ASN.2016030368. Epub 2016 Aug 4.PMID: 27493255

Adherence to and Acceptance of Once-Daily Tacrolimus After Kidney and Liver Transplant: Results From OSIRIS, a French Observational Study.
Cassuto E, Pageaux GP, Cantarovich D, Rostaing L, Loupy A, Roche B, Duvoux C, Moreau K, Thervet E, Mazouz H, Bourhis Y, Dharancy S, Kessler M; OSIRIS investigators.
Transplantation. 2016 Oct;100(10):2099-2106. doi: 10.1097/TP.0000000000001307.PMID: 27653227

Early Identification of Patients With Out-of-Hospital Cardiac Arrest With No Chance of Survival and Consideration for Organ Donation.
Jabre P, Bougouin W, Dumas F, Carli P, Antoine C, Jacob L, Dahan B, Beganton F, Empana JP, Marijon E, Karam N, Loupy A, Lefaucheur C, Jost D, Cariou A, Adnet F, Rea TD, Jouven X.
Ann Intern Med. 2016 Dec 6;165(11):770-778. doi: 10.7326/M16-0402. Epub 2016 Sep 13.PMID: 27618681

Donor-specific antibodies and antibody-mediated rejection in vascularized composite allotransplantation.
Weissenbacher A, Loupy A, Chandraker A, Schneeberger S.
Curr Opin Organ Transplant. 2016 Oct;21(5):510-5. doi: 10.1097/MOT.0000000000000349.PMID: 27517505 Review.

Value of Donor-Specific Anti-HLA Antibody Monitoring and Characterization for Risk Stratification of Kidney Allograft Loss.
Viglietti D, Loupy A, Vernerey D, Bentlejewski C, Gosset C, Aubert O, Duong van Huyen JP, Jouven X, Legendre C, Glotz D, Zeevi A, Lefaucheur C.
J Am Soc Nephrol. 2017 Feb;28(2):702-715. doi: 10.1681/ASN.2016030368. Epub 2016 Aug 4.PMID: 27493255

IgG Donor-Specific Anti-Human HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated Injury.
Lefaucheur C, Viglietti D, Bentlejewski C, Duong van Huyen JP, Vernerey D, Aubert O, Verine J, Jouven X, Legendre C, Glotz D, Loupy A, Zeevi A.
J Am Soc Nephrol. 2016 Jan;27(1):293-304. doi: 10.1681/ASN.2014111120. Epub 2015 Aug 20.PMID: 26293822

Focal Segmental Glomerulosclerosis Recurrence: Soluble Urokinase Receptor Left Out?
Canaud G, Loupy A.
Transplantation. 2015 Dec;99(12):2449-50. doi: 10.1097/TP.0000000000000923.PMID: 26371599

IgG Donor-Specific Anti-Human HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated Injury.
Lefaucheur C, Viglietti D, Bentlejewski C, Duong van Huyen JP, Vernerey D, Aubert O, Verine J, Jouven X, Legendre C, Glotz D, Loupy A, Zeevi A.
J Am Soc Nephrol. 2016 Jan;27(1):293-304. doi: 10.1681/ASN.2014111120. Epub 2015 Aug 20.PMID: 26293822

Long term outcomes of transplantation using kidneys from expanded criteria donors: prospective, population based cohort study.
Aubert O, Kamar N, Vernerey D, Viglietti D, Martinez F, Duong-Van-Huyen JP, Eladari D, Empana JP, Rabant M, Verine J, Rostaing L, Congy N, Guilbeau-Frugier C, Mourad G, Garrigue V, Morelon E, Giral M, Kessler M, Ladrière M, Delahousse M, Glotz D, Legendre C, Jouven X, Lefaucheur C, Loupy A.
BMJ. 2015 Jul 31;351:h3557. doi: 10.1136/bmj.h3557.PMID: 26232393 Clinical Trial.

Determinants and Outcomes of Accelerated Arteriosclerosis: Major Impact of Circulating Antibodies.
Loupy A, Vernerey D, Viglietti D, Aubert O, Duong Van Huyen JP, Empana JP, Bruneval P, Glotz D, Legendre C, Jouven X, Lefaucheur C.
Circ Res. 2015 Aug 14;117(5):470-82. doi: 10.1161/CIRCRESAHA.117.306340. Epub 2015 Jun 8.PMID: 26056252

From Mean Fluorescence Intensity to C1q-Binding: The Saga of Anti-HLA Donor-specific Antibodies.
Loupy A, Legendre C.
Transplantation. 2015 Jun;99(6):1107-8. doi: 10.1097/TP.0000000000000700.PMID: 25839710 No abstract available.

Subclinical Rejection Phenotypes at 1 Year Post-Transplant and Outcome of Kidney Allografts.
Loupy A, Vernerey D, Tinel C, Aubert O, Duong van Huyen JP, Rabant M, Verine J, Nochy D, Empana JP, Martinez F, Glotz D, Jouven X, Legendre C, Lefaucheur C.
J Am Soc Nephrol. 2015 Jul;26(7):1721-31. doi: 10.1681/ASN.2014040399. Epub 2015 Jan 2.PMID: 25556173

De Novo Donor-Specific Human Leukocyte Antigen Antibodies in Nonsensitized Kidney Transplant Recipients After T Cell-Mediated Rejection.
Chemouny JM, Suberbielle C, Rabant M, Zuber J, Alyanakian MA, Lebreton X, Carmagnat M, Pinheiro N, Loupy A, Van Huyen JP, Timsit MO, Charron D, Legendre C, Anglicheau D.
Transplantation. 2015 May;99(5):965-72. doi: 10.1097/TP.0000000000000448.PMID: 25340597

Kidney allograft fibrosis after transplantation from uncontrolled circulatory death donors.
Viglietti D, Abboud I, Hill G, Vernerey D, Nochy D, Antoine C, Fieux F, Assayag M, Verine J, Gaudez F, Loupy A, Glotz D, Lefaucheur C.
​Transplantation. 2015 Feb;99(2):409-15. doi: 10.1097/TP.0000000000000228.PMID: 25222117

[Current aspects of acute humoral rejection].
Legendre C, Loupy A, Rabant M, Aubert O, Rabaté C, Delville M, Tinel C, Amrouche L, Martinez F, Snanoudj R, Bererhi L, Scemla A, Sberro-Soussan R, Duong JP, Suberbielle C, Anglicheau D.
Nephrol Ther. 2014 Nov;10(6):479-83. doi: 10.1016/j.nephro.2014.09.001. Epub 2014 Oct 16.PMID: 25440942 Review. French.

MicroRNAs as non-invasive biomarkers of heart transplant rejection.
Duong Van Huyen JP, Tible M, Gay A, Guillemain R, Aubert O, Varnous S, Iserin F, Rouvier P, François A, Vernerey D, Loyer X, Leprince P, Empana JP, Bruneval P, Loupy A, Jouven X.
Eur Heart J. 2014 Dec 1;35(45):3194-202. doi: 10.1093/eurheartj/ehu346. Epub 2014 Aug 31.PMID: 25176944 Clinical Trial.

Molecular microscope strategy to improve risk stratification in early antibody-mediated kidney allograft rejection.
Loupy A, Lefaucheur C, Vernerey D, Chang J, Hidalgo LG, Beuscart T, Verine J, Aubert O, Dubleumortier S, Duong van Huyen JP, Jouven X, Glotz D, Legendre C, Halloran PF.
J Am Soc Nephrol. 2014 Oct;25(10):2267-77. doi: 10.1681/ASN.2013111149. Epub 2014 Apr 3.PMID: 24700874

Complement-binding anti-HLA antibodies and kidney transplantation.
Lefaucheur C, Loupy A, Zeevi A.
N Engl J Med. 2014 Jan 2;370(1):85-6. doi: 10.1056/NEJMc1313506.PMID: 24382075

A kidney transplant patient with ileocecal inflammation. Sodium polystyrene sulfonate-associated intestinal ulcer and foreign-body reaction.
Zaidan M, Loupy A, Rouquette A, Philippe Massault P, Martinez F, Legendre C, Mamzer-Bruneel MF.
Kidney Int. 2013 Nov;84(5):1057-9. doi: 10.1038/ki.2013.146.PMID: 24172749 

Complement-binding anti-HLA antibodies and kidney-allograft survival.
Loupy A, Lefaucheur C, Vernerey D, Prugger C, Duong van Huyen JP, Mooney N, Suberbielle C, Frémeaux-Bacchi V, Méjean A, Desgrandchamps F, Anglicheau D, Nochy D, Charron D, Empana JP, Delahousse M, Legendre C, Glotz D, Hill GS, Zeevi A, Jouven X.
N Engl J Med. 2013 Sep 26;369(13):1215-26. doi: 10.1056/NEJMoa1302506.PMID: 24066742

Pathologic classification of antibody-mediated rejection correlates with donor-specific antibodies and endothelial cell activation.
Tible M, Loupy A, Vernerey D, Suberbielle C, Beuscart T, Cazes A, Guillemain R, Amrein C, Pezzella V, Fabiani JN, Nochy D, Hill G, Empana JP, Jouven X, Charron D, Bruneval P, Duong Van Huyen JP.
J Heart Lung Transplant. 2013 Aug;32(8):769-76. doi: 10.1016/j.healun.2013.05.012.PMID: 23856214

Eculizumab in renal transplantation.
Legendre C, Sberro-Soussan R, Zuber J, Rabant M, Loupy A, Timsit MO, Anglicheau D.
Transplant Rev (Orlando). 2013 Jul;27(3):90-2. doi: 10.1016/j.trre.2013.04.002. Epub 2013 Jun 7.PMID: 23747093 Review.

Transplantation: Donor-specific HLA antibodies and renal allograft failure.
Loupy A, Jordan SC.
Nat Rev Nephrol. 2013 Mar;9(3):130-1. doi: 10.1038/nrneph.2013.18. Epub 2013 Feb 12.PMID: 23399581

Influence of fractalkine receptor gene polymorphisms V249I-T280M on cancer occurrence after renal transplantation.
Courivaud C, Bamoulid J, Loupy A, Deschamps M, Ferrand C, Simula-Faivre D, Tiberghien P, Chalopin JM, Legendre C, Thervet E, Borg C, Saas P, Ducloux D.
Transplantation. 2013 Mar 15;95(5):728-32. doi: 10.1097/TP.0b013e31827d61cb.PMID: 23388733

Antibody-mediated vascular rejection of kidney allografts: a population-based study.
Lefaucheur C, Loupy A, Vernerey D, Duong-Van-Huyen JP, Suberbielle C, Anglicheau D, Vérine J, Beuscart T, Nochy D, Bruneval P, Charron D, Delahousse M, Empana JP, Hill GS, Glotz D, Legendre C, Jouven X.
​Lancet. 2013 Jan 26;381(9863):313-9. doi: 10.1016/S0140-6736(12)61265-3. Epub 2012 Nov 23.PMID: 23182298

Antibody-mediated vascular rejection of kidney allografts: a population-based study.
Lefaucheur C, Loupy A, Vernerey D, Duong-Van-Huyen JP, Suberbielle C, Anglicheau D, Vérine J, Beuscart T, Nochy D, Bruneval P, Charron D, Delahousse M, Empana JP, Hill GS, Glotz D, Legendre C, Jouven X.
Lancet. 2013 Jan 26;381(9863):313-9. doi: 10.1016/S0140-6736(12)61265-3. Epub 2012 Nov 23.PMID: 23182298

PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor.
Loupy A, Ramakrishnan SK, Wootla B, Chambrey R, de la Faille R, Bourgeois S, Bruneval P, Mandet C, Christensen EI, Faure H, Cheval L, Laghmani K, Collet C, Eladari D, Dodd RH, Ruat M, Houillier P.
J Clin Invest. 2012 Sep;122(9):3355-67. doi: 10.1172/JCI57407. Epub 2012 Aug 13.PMID: 22886306

The impact of donor-specific anti-HLA antibodies on late kidney allograft failure.
Loupy A, Hill GS, Jordan SC.
Nat Rev Nephrol. 2012 Apr 17;8(6):348-57. doi: 10.1038/nrneph.2012.81.PMID: 22508180 Review.

A clinicopathologic study of thrombotic microangiopathy in IgA nephropathy.
El Karoui K, Hill GS, Karras A, Jacquot C, Moulonguet L, Kourilsky O, Frémeaux-Bacchi V, Delahousse M, Duong Van Huyen JP, Loupy A, Bruneval P, Nochy D.
J Am Soc Nephrol. 2012 Jan;23(1):137-48. doi: 10.1681/ASN.2010111130. Epub 2011 Nov 3.PMID: 22052055

Kidney function following nephrectomy: similitude and discrepancies between kidney cancer and living donation.
Timsit MO, Nguyen KN, Rouach Y, Elie C, Loupy A, Fournier C, Legendre C, Mejean A.
​Urol Oncol. 2012 Jul-Aug;30(4):482-6. doi: 10.1016/j.urolonc.2010.04.005. Epub 2010 Sep 22.PMID: 20864365

A clinicopathologic study of thrombotic microangiopathy in IgA nephropathy.
El Karoui K, Hill GS, Karras A, Jacquot C, Moulonguet L, Kourilsky O, Frémeaux-Bacchi V, Delahousse M, Duong Van Huyen JP, Loupy A, Bruneval P, Nochy D.
J Am Soc Nephrol. 2012 Jan;23(1):137-48. doi: 10.1681/ASN.2010111130. Epub 2011 Nov 3.PMID: 22052055

Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy. II. Light microscopic and clinical studies.
El Karoui K, Hill GS, Karras A, Moulonguet L, Caudwell V, Loupy A, Bruneval P, Jacquot C, Nochy D.
Kidney Int. 2011 Mar;79(6):643-654. doi: 10.1038/ki.2010.460. Epub 2010 Dec 22.PMID: 21178978
 
Incidence of infectious complications in highly sensitized renal transplant recipients treated by rituximab: a case-controlled study.
Scemla A, Loupy A, Candon S, Mamzer MF, Martinez F, Zuber J, Sberro R, Legendre C, Thervet E.
Transplantation. 2010 Dec 15;90(11):1180-4. doi: 10.1097/TP.0b013e3181fa941b.PMID: 20885337
 
Kidney function following nephrectomy: similitude and discrepancies between kidney cancer and living donation.
Timsit MO, Nguyen KN, Rouach Y, Elie C, Loupy A, Fournier C, Legendre C, Mejean A.
Urol Oncol. 2012 Jul-Aug;30(4):482-6. doi: 10.1016/j.urolonc.2010.04.005. Epub 2010 Sep 22.PMID: 20864365
 
Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation.
Lefaucheur C, Loupy A, Hill GS, Andrade J, Nochy D, Antoine C, Gautreau C, Charron D, Glotz D, Suberbielle-Boissel C.
J Am Soc Nephrol. 2010 Aug;21(8):1398-406. doi: 10.1681/ASN.2009101065. Epub 2010 Jul 15.PMID: 20634297
 
Influence of cyclooxygenase-2 (COX-2) gene promoter polymorphism at position -765 on skin cancer after renal transplantation.
Aubin F, Courivaud C, Bamoulid J, Loupy A, Deschamps M, Ferrand C, Le Corre D, Tiberghien P, Chalopin JM, Legendre C, Thervet E, Humbert P, Saas P, Ducloux D.
J Invest Dermatol. 2010 Aug;130(8):2134-6. doi: 10.1038/jid.2010.116. Epub 2010 May 6.PMID: 20445548
 
Combined posttransplant prophylactic IVIg/anti-CD 20/plasmapheresis in kidney recipients with preformed donor-specific antibodies: a pilot study.
Loupy A, Suberbielle-Boissel C, Zuber J, Anglicheau D, Timsit MO, Martinez F, Thervet E, Bruneval P, Charron D, Hill GS, Nochy D, Legendre C.
Transplantation. 2010 Jun 15;89(11):1403-10. doi: 10.1097/TP.0b013e3181da1cc3.PMID: 20386362

Accelerated arteriosclerosis: a form of transplant arteriopathy.
Hill GS, Nochy D, Loupy A.
Curr Opin Organ Transplant. 2010 Feb;15(1):11-5. doi: 10.1097/MOT.0b013e3283342684.PMID: 19898238 Review.

Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy. II. Light microscopic and clinical studies.
El Karoui K, Hill GS, Karras A, Moulonguet L, Caudwell V, Loupy A, Bruneval P, Jacquot C, Nochy D.
Kidney Int. 2011 Mar;79(6):643-654. doi: 10.1038/ki.2010.460. Epub 2010 Dec 22.PMID: 21178978
 
Incidence of infectious complications in highly sensitized renal transplant recipients treated by rituximab: a case-controlled study.
Scemla A, Loupy A, Candon S, Mamzer MF, Martinez F, Zuber J, Sberro R, Legendre C, Thervet E.
Transplantation. 2010 Dec 15;90(11):1180-4. doi: 10.1097/TP.0b013e3181fa941b.PMID: 20885337
 
Kidney function following nephrectomy: similitude and discrepancies between kidney cancer and living donation.
Timsit MO, Nguyen KN, Rouach Y, Elie C, Loupy A, Fournier C, Legendre C, Mejean A.
Urol Oncol. 2012 Jul-Aug;30(4):482-6. doi: 10.1016/j.urolonc.2010.04.005. Epub 2010 Sep 22.PMID: 20864365
 
Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation.
Lefaucheur C, Loupy A, Hill GS, Andrade J, Nochy D, Antoine C, Gautreau C, Charron D, Glotz D, Suberbielle-Boissel C.
J Am Soc Nephrol. 2010 Aug;21(8):1398-406. doi: 10.1681/ASN.2009101065. Epub 2010 Jul 15.PMID: 20634297
 
Influence of cyclooxygenase-2 (COX-2) gene promoter polymorphism at position -765 on skin cancer after renal transplantation.
Aubin F, Courivaud C, Bamoulid J, Loupy A, Deschamps M, Ferrand C, Le Corre D, Tiberghien P, Chalopin JM, Legendre C, Thervet E, Humbert P, Saas P, Ducloux D.
J Invest Dermatol. 2010 Aug;130(8):2134-6. doi: 10.1038/jid.2010.116. Epub 2010 May 6.PMID: 20445548
 
Combined posttransplant prophylactic IVIg/anti-CD 20/plasmapheresis in kidney recipients with preformed donor-specific antibodies: a pilot study.
Loupy A, Suberbielle-Boissel C, Zuber J, Anglicheau D, Timsit MO, Martinez F, Thervet E, Bruneval P, Charron D, Hill GS, Nochy D, Legendre C.
Transplantation. 2010 Jun 15;89(11):1403-10. doi: 10.1097/TP.0b013e3181da1cc3.PMID: 20386362

Accelerated arteriosclerosis: a form of transplant arteriopathy.
Hill GS, Nochy D, Loupy A.
Curr Opin Organ Transplant. 2010 Feb;15(1):11-5. doi: 10.1097/MOT.0b013e3283342684.PMID: 19898238 Review.

Tissue compartment analysis for biomarker discovery by gene expression profiling.
Disset A, Cheval L, Soutourina O, Duong Van Huyen JP, Li G, Genin C, Tostain J, Loupy A, Doucet A, Rajerison R.
PLoS One. 2009 Nov 10;4(11):e7779. doi: 10.1371/journal.pone.0007779.PMID: 19901995

Urogenital mycoplasma: an emerging cause of deep wound infection after kidney transplantation?
Loupy A, Join-Lambert OF, Bébéar CM, Legendre C, Anglicheau D.
NDT Plus. 2008 Aug;1(4):239-40. doi: 10.1093/ndtplus/sfn053. Epub 2008 May 25.PMID: 25983892
 
High-dosage intravenous immunoglobulin-associated macrovacuoles are associated with chronic tubulointerstitial lesion worsening in renal transplant recipients.
Bollée G, Anglicheau D, Loupy A, Zuber J, Patey N, Mac Gregor D, Martinez F, Mamzer-Bruneel MF, Snanoudj R, Thervet E, Legendre C, Noël LH.
Clin J Am Soc Nephrol. 2008 Sep;3(5):1461-8. doi: 10.2215/CJN.00500108. Epub 2008 Jun 4.PMID: 18525007

Long-term outcome of third kidney transplants.
Loupy A, Anglicheau D, Suberbielle C, Méjean A, Martinez F, Zuber J, Mamzer-Bruneel MF, Kreis H, Thervet E, Thiounn N, Legendre C.
Nephrol Dial Transplant. 2007 Sep;22(9):2693-700. doi: 10.1093/ndt/gfm226. Epub 2007 Apr 23.PMID: 17452406

Impact of surgical procedures and complications on outcomes of third and subsequent kidney transplants.
Loupy A, Anglicheau D, Timsit MO, Thervet E, Mamzer-Bruneel MF, Martinez F, Desgranchamps F, Thiounn N, Kreis H, Legendre C, Chrétien Y, Méjean A.

Mycophenolate sodium-induced hepatotoxicity: first report.
Loupy A, Anglicheau D, Mamzer-Bruneel MF, Martinez F, Thervet E, Legendre C, Serpaggi J, Pol S.
Transplantation. 2006 Aug 27;82(4):581. doi: 10.1097/01.tp.0000231873.86048.68.PMID: 16926609